Section: New Software and Platforms

Nenuphar

Keywords: Modeling - Oncologie - Cancer - Partial differential equation - Medical - Medical imaging

• Partners: CNRS - INP Bordeaux - Université Bordeaux 1

• Contact: Marie Martin

• Functional Description The goal of project is to evaluate the aggressiveness of a tumor or its response to therapy. For that purpose, we use a mathematical model based on a set of nonlinear partial differential equations. This model is calibrated on patient data using a longitudinal sequence of CT Scan or MRI of the patient. This approach has been validated on about 35 clinical cases of lung metastases from various primary tumors (kidney, bladder, thyroid). Using two initial images showing the targeted lesion, we recover the patient-specific parameters of the model. The evolution of the disease is then predicted by letting the model run for later times with these parameters.